eLife· 2026Q1

A biochemical mechanism for Stu2/XMAP215-family microtubule polymerases

Binnu Gangadharan, Daniel L. Kober, Luke M. Rice

1citations
Q1SCImago
2026year

Short summary

A quantitative biochemical model shows Stu2/XMAP215-family polymerases act as tubulin-shuttling antennas, with activity limited by tubulin:TOG association rates.

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Cell BiologyBiochemistry, Genetics and Molecular Biology