The Journal of Headache and Pain· 2026Q1· Review
Multidimensional mechanisms of the trigeminal–limbic axis underlying TMD–anxiety comorbidity—a narrative review
- 0citations
- Q1SCImago
- 2026year
Short summary
A narrative review proposes the trigeminal-limbic axis, specifically the TG-Vc-PBN-CeA pathway, as a candidate circuit linking temporomandibular disorder (TMD) pain to anxiety, supported by evidence from chronic pain and anxiety models.
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