PofoliaShared via Pofolia

Proceedings of the National Academy of Sciences· 2026Q1

SelO functions as a tumor suppressor through AMPylating Cdk5rap3

Li Wu, Jie Wu, Wenqiang Xie, Xue Lü et al.

Short summary

SELENOO (SelO) protein, induced by chemotherapy, suppresses tumor growth and metastasis by AMPylating Cdk5rap3, thereby destabilizing Mdm2 and Slug proteins.

AI-generated from the title and abstract; the full text is not read.

TakeawaysIn the app
Key pointsIn the app
Ask the paperIn the app

The rest is in the Pofolia app

Takeaways, key points and questions to the paper; new summaries every day for your field. Free.

Sign in on the web to open

Field: Rheumatology

RheumatologyMedicine