Key papers in Rheumatology
Pofolia’s corpus holds 57 papers from the Rheumatology subfield (2012–2025). The list below starts with the most cited.
Most cited
Ranked by citation count. Because citations accumulate over time, this list naturally leans towards work published a few years ago; for where the field is now, see “recently added”.
Derivation and validation of the Systemic Lupus International Collaborating Clinics classification criteria for systemic lupus erythematosus
Arthritis & Rheumatism · 2012 · FWCI 98.74 · 5,321 citations
New Systemic Lupus International Collaborating Clinics (SLICC) classification criteria for lupus have been developed and validated, showing improved sensitivity and fewer misclassifications compared to previous ACR criteria.
Osteoarthritis: A disease of the joint as an organ
Arthritis & Rheumatism · 2012 · FWCI 58.57 · 3,091 citations
Osteoarthritis (OA) is reframed from a "degenerative joint disease" to a complex disease involving abnormal remodeling of all joint tissues, driven by inflammatory mediators, leading to "joint failure."
American College of Rheumatology 2012 recommendations for the use of nonpharmacologic and pharmacologic therapies in osteoarthritis of the hand, hip, and knee
Arthritis Care & Research · 2012 · Q1 · SJR 1.00 · FWCI 168.89 · 3,091 citations · Open access
New guidelines from the American College of Rheumatology offer conditional and strong recommendations for managing osteoarthritis (OA) in the hand, hip, and knee, incorporating both non-pharmacologic and pharmacologic therapies.
2015 American College of Rheumatology Guideline for the Treatment of Rheumatoid Arthritis
Arthritis & Rheumatology · 2015 · Q1 · SJR 4.00 · FWCI 215.33 · 2,792 citations
A new evidence-based guideline offers 74 recommendations for pharmacologic treatment of rheumatoid arthritis (RA), distinguishing between strong and conditional advice based on benefit-harm balance and patient preferences.
Campbell-Walsh urology
Elsevier eBooks · 2012 · FWCI 115.70 · 2,713 citations
This abstract outlines the comprehensive structure of the Campbell-Walsh Urology textbook, detailing its extensive coverage of urologic anatomy, clinical decision-making, surgical techniques, and various disease states.
IgG4-Related Disease
New England Journal of Medicine · 2012 · Q1 · SJR 18.00 · FWCI 155.25 · 2,606 citations
This review outlines the diverse range of autoimmune diseases now understood to be linked with IgG4 autoantibodies.
2019 European League Against Rheumatism/American College of Rheumatology Classification Criteria for Systemic Lupus Erythematosus
Arthritis & Rheumatology · 2019 · Q1 · SJR 4.00 · FWCI 146.04 · 2,554 citations · Open access
New classification criteria for Systemic Lupus Erythematosus (SLE) have been developed, requiring a positive Antinuclear Antibody (ANA) test as an entry point, followed by additive weighted criteria across clinical and immunologic domains.
2019 American College of Rheumatology/Arthritis Foundation Guideline for the Management of Osteoarthritis of the Hand, Hip, and Knee
Arthritis Care & Research · 2020 · Q1 · SJR 1.00 · FWCI 242.44 · 2,502 citations · Open access
New guidelines offer strong recommendations for exercise, weight loss, self-management programs, and tai chi for hand, hip, and knee osteoarthritis.
Diagnosis and Management of Rheumatoid Arthritis
JAMA · 2018 · Q1 · SJR 5.00 · FWCI 107.57 · 2,313 citations
Early diagnosis and treatment of Rheumatoid Arthritis (RA) can prevent irreversible joint damage and disability in up to 90% of patients. A treat-to-target strategy, aiming for remission or low disease activity within 6 months, is key to improved outcomes.
Diagnosis and Treatment of Hip and Knee Osteoarthritis
JAMA · 2021 · Q1 · SJR 5.00 · FWCI 223.03 · 2,279 citations
Hip and knee osteoarthritis (OA) are highly prevalent and disabling conditions affecting over 240 million people globally, characterized by joint pain, stiffness, and functional limitation.
Coagulopathy and Antiphospholipid Antibodies in Patients with Covid-19
New England Journal of Medicine · 2020 · Q1 · SJR 18.00 · FWCI 332.58 · 2,259 citations
Three critically ill patients with COVID-19 presented with coagulopathy and antiphospholipid antibodies.
Revised procedures for staining and clearing small fishes and other vertebrates for bone and cartilage study
Société Française d'Ichtyologie · 2023 · FWCI 33.33 · 1,989 citations
A new protocol for staining bone and cartilage in small vertebrates minimizes damage by altering the dehydration and deacidification steps, improving preservation of delicate structures.
2019 American College of Rheumatology/Arthritis Foundation Guideline for the Management of Osteoarthritis of the Hand, Hip, and Knee
Arthritis & Rheumatology · 2020 · Q1 · SJR 4.00 · FWCI 169.45 · 1,959 citations · Open access
New guidelines offer strong recommendations for exercise, weight loss, self-management programs, tai chi, and specific bracing/injections for osteoarthritis (OA) of the hand, hip, and knee.
2012 Update of the 2008 American College of Rheumatology recommendations for the use of disease‐modifying antirheumatic drugs and biologic agents in the treatment of rheumatoid arthritis
Arthritis Care & Research · 2012 · Q1 · SJR 1.00 · FWCI 167.03 · 1,803 citations · Open access
Updated guidelines provide recommendations for using conventional synthetic, targeted synthetic, and biologic disease-modifying antirheumatic drugs (DMARDs) for rheumatoid arthritis (RA) treatment.
Global, regional, and national burden of osteoarthritis, 1990–2020 and projections to 2050: a systematic analysis for the Global Burden of Disease Study 2021
The Lancet Rheumatology · 2023 · Q1 · SJR 6.00 · FWCI 349.41 · 1,797 citations · Open access
Osteoarthritis cases surged 132% globally from 1990 to 2020, affecting 595 million people, and are projected to increase by nearly 75% by 2050 due to population aging and growth.
Rheumatoid arthritis: pathological mechanisms and modern pharmacologic therapies
Bone Research · 2018 · Q1 · SJR 4.00 · FWCI 97.44 · 1,775 citations · Open access
This review dissects the pathological mechanisms of rheumatoid arthritis (RA) across its four stages and discusses current and emerging pharmacologic therapies aimed at achieving disease remission.
Cardiovascular and Cancer Risk with Tofacitinib in Rheumatoid Arthritis
New England Journal of Medicine · 2022 · Q1 · SJR 18.00 · FWCI 229.91 · 1,733 citations · Open access
Tofacitinib, a drug for rheumatoid arthritis, was found to increase the risk of major adverse cardiovascular events (MACE) and cancers compared to TNF inhibitors. The drug did not meet noninferiority criteria for safety.
Comprehensive diagnostic criteria for IgG4-related disease (IgG4-RD), 2011
Modern Rheumatology · 2012 · Q2 · FWCI 98.18 · 1,657 citations
New comprehensive diagnostic criteria for IgG4-related disease (IgG4-RD) have been established, combining serum IgG4 concentration and biopsy findings.
The Role of Tumor Necrosis Factor Alpha (TNF-α) in Autoimmune Disease and Current TNF-α Inhibitors in Therapeutics
International Journal of Molecular Sciences · 2021 · Q1 · SJR 1.00 · FWCI 144.06 · 1,636 citations · Open access
Tumor Necrosis Factor Alpha (TNF-α) signaling, initially known for tumor necrosis, is now understood as a key pathological driver in autoimmune diseases due to its role in chronic inflammation.
The Role of Inflammatory and Anti-Inflammatory Cytokines in the Pathogenesis of Osteoarthritis
Mediators of Inflammation · 2014 · Q2 · SJR 1.00 · FWCI 42.86 · 1,612 citations · Open access
Osteoarthritis (OA) pathogenesis involves a complex interplay of inflammatory and anti-inflammatory cytokines, with inflammatory cytokines like IL-1β and TNFα playing a key role alongside anabolic processes.
Recently added
Factors, characteristics and influences of the changes of muscle activation patterns for patients with knee osteoarthritis: a review
Journal of Orthopaedic Surgery and Research · 2025 · Q1 · SJR 1.00 · FWCI 22.57 · 26 citations · Open access
Knee osteoarthritis (KOA) patients exhibit altered muscle activation patterns (MAP), including larger activation amplitudes and earlier/longer activation times in vastus lateralis (VL) and biceps femoris (BF), and delayed activation in vastus medialis (VM).
Does Higher Compliance With American College of Sports Medicine Exercise Prescription Guidelines Influence Exercise Outcomes in Knee Osteoarthritis? A Systematic Review With Meta‐Analysis
Arthritis Care & Research · 2024 · FWCI 1.28 · 7 citations
Higher compliance (≥60%) with American College of Sports Medicine exercise guidelines did not lead to better pain or function outcomes in knee osteoarthritis patients compared to lower compliance (<60%), according to a meta-analysis of 103 trials.
Revised procedures for staining and clearing small fishes and other vertebrates for bone and cartilage study
Société Française d'Ichtyologie · 2023 · FWCI 33.33 · 1,989 citations
A new protocol for staining bone and cartilage in small vertebrates minimizes damage by altering the dehydration and deacidification steps, improving preservation of delicate structures.
Global, regional, and national burden of osteoarthritis, 1990–2020 and projections to 2050: a systematic analysis for the Global Burden of Disease Study 2021
The Lancet Rheumatology · 2023 · Q1 · SJR 6.00 · FWCI 349.41 · 1,797 citations · Open access
Osteoarthritis cases surged 132% globally from 1990 to 2020, affecting 595 million people, and are projected to increase by nearly 75% by 2050 due to population aging and growth.
Osteoarthritis: pathogenic signaling pathways and therapeutic targets
Signal Transduction and Targeted Therapy · 2023 · Q1 · SJR 17.00 · FWCI 210.91 · 1,090 citations · Open access
This review details key signaling pathways (Wnt/β-catenin, NF-κB, focal adhesion, HIFs, TGFβ/BMP, FGF) and regulators (AMPK, mTOR, RUNX2) implicated in osteoarthritis (OA) pathogenesis, highlighting their roles in the chronic degenerative joint disorder.
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