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Clinical Biochemist Reviews· 2019Q4

Inductively Coupled Plasma Mass Spectrometry: Introduction to Analytical Aspects

Scott Wilschefski, Matthew Baxter

Short summary

Inductively coupled plasma mass spectrometry (ICP-MS) is increasingly replacing older methods for measuring trace elements in biological fluids due to its sensitivity.

AI-generated from the title and abstract; the full text is not read.

Key points

  • ICP-MS measures elements at trace levels in biological fluids.
  • It is gradually replacing older techniques like atomic absorption and emission.
  • Awareness of analytical aspects and interferences is crucial for clinical scientists.
  • Strategies exist to eliminate or mitigate spectroscopic and non-spectroscopic interferences.

AI-generated from the title and abstract; the full text is not read.

Abstract

Inductively coupled plasma mass spectrometry (ICP-MS) is an analytical technique that can be used to measure elements at trace levels in biological fluids. Although older techniques such as atomic absorption and atomic emission are still in use by some laboratories, there has been a slow shift toward ICP-MS, particularly in the last decade. As this shift is likely to continue, clinical scientists should be aware of the analytical aspects of ICP-MS, as well as the potential for both spectroscopic and non-spectroscopic interference, and strategies that can be employed to eliminate or mitigate these issues.

The authors' abstract, as published at the source. Clinical Biochemist Reviews, 2019 · DOI ↗

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Field: Analytical Chemistry

Analytical ChemistryChemistry