Journal of Medicinal Chemistry· 2018Q1· Review
Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design
- 2,565citations
- Q1SCImago
- 2018year
Short summary
Fluorine's unique electronic properties and small size make it a versatile bioisostere, enabling substitution for various atoms and functional groups to enhance drug properties like potency and metabolism.
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Organic ChemistryChemistry