Organic Chemistry papers
Pofolia’s corpus holds 115 papers from Organic Chemistry (2012–2026), each with a short summary. Below, the 20 most-cited, then the most recently added.
At a glance
- Most cited: CRC Handbook of Chemistry and Physics (2014, 57,892 citations).
- The 20 papers listed have 139,335 citations between them.
- 17 of the 18 with a known journal quartile appeared in a Q1 journal.
- 1 have a free full text (open access).
- Most frequent journals: Chemical Reviews, Angewandte Chemie International Edition, Journal of Medicinal Chemistry.
- Published between 2012 and 2018.
Most cited
Ranked by citation count. Because citations accumulate over time, this list naturally leans towards work published a few years ago; for where the field is now, see “recently added”. How to read the signals
CRC Handbook of Chemistry and Physics
2014 · FWCI 245.31 · 57,892 citations
The 95th edition of the CRC Handbook of Chemistry and Physics has been released, continuing its legacy as a classic and highly respected scientific reference.
Visible Light Photoredox Catalysis with Transition Metal Complexes: Applications in Organic Synthesis
Chemical Reviews · 2013 · Q1 · SJR 16.00 · FWCI 218.39 · 9,451 citations
This review details the burgeoning field of visible light photoredox catalysis, highlighting how transition metal complexes can harness light energy to drive a wide array of organic transformations.
Free Radicals in Biology and Medicine
Oxford University Press eBooks · 2015 · FWCI 172.00 · 8,905 citations
This thoroughly revised edition offers a comprehensive account of the role of free radicals, reactive species (RS), and antioxidants in life, health, and disease.
In situ click chemistry generation of cyclooxygenase-2 inhibitors
Nature Communications · 2017 · Q1 · SJR 4.00 · FWCI 252.60 · 7,562 citations · Open access
Researchers developed a novel method using the cyclooxygenase-2 (COX-2) enzyme's active site as a reaction vessel to generate highly specific COX-2 inhibitors via in situ click chemistry.
Analysis of the Structural Diversity, Substitution Patterns, and Frequency of Nitrogen Heterocycles among U.S. FDA Approved Pharmaceuticals
Journal of Medicinal Chemistry · 2014 · Q1 · SJR 1.00 · FWCI 69.81 · 6,286 citations
Nitrogen heterocycles are crucial in drug design, with 59% of U.S. FDA-approved small-molecule drugs containing them.
Organic Photoredox Catalysis
Chemical Reviews · 2016 · Q1 · SJR 16.00 · FWCI 366.49 · 6,221 citations
This review highlights the diverse synthetic transformations enabled by organic photoredox catalysts, detailing their photophysical and electrochemical properties.
Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)
Chemical Reviews · 2013 · Q1 · SJR 16.00 · FWCI 126.96 · 4,762 citations
Over 20% of the top 200 drugs sold in 2011 contained fluorine, with a significant portion of new drug approvals featuring this element.
Synthetic Organic Electrochemical Methods Since 2000: On the Verge of a Renaissance
Chemical Reviews · 2017 · Q1 · SJR 16.00 · FWCI 105.93 · 3,784 citations
Synthetic organic electrochemistry has seen significant advances since 2000, moving towards a renaissance by enabling new molecular interactions and synthetic applications.
Self-assembly of block copolymers
Chemical Society Reviews · 2012 · Q1 · SJR 11.00 · FWCI 74.72 · 3,550 citations
Block copolymers (BCPs) self-assemble into diverse ordered structures like spheres, cylinders, and lamellae, offering potential applications across various fields.
Photoredox Catalysis in Organic Chemistry
The Journal of Organic Chemistry · 2016 · Q2 · FWCI 208.53 · 3,163 citations
Photoredox catalysis uses visible light to drive chemical reactions by generating reactive intermediates through single-electron transfer, enabling novel reaction mechanisms.
Palladium‐Catalyzed Cross‐Coupling: A Historical Contextual Perspective to the 2010 Nobel Prize
Angewandte Chemie International Edition · 2012 · Q1 · SJR 5.00 · FWCI 76.34 · 2,974 citations
This review traces the historical origins and development of palladium-catalyzed cross-coupling reactions, which revolutionized C-C bond construction and earned Heck, Negishi, and Suzuki the 2010 Nobel Prize in Chemistry.
CH Bond Functionalization: Emerging Synthetic Tools for Natural Products and Pharmaceuticals
Angewandte Chemie International Edition · 2012 · Q1 · SJR 5.00 · FWCI 122.00 · 2,966 citations
Direct C-H bond functionalization is an emerging, powerful method for creating carbon-carbon and carbon-heteroatom bonds, offering an ideal route for synthesizing complex molecules.
Oxidative stress: a concept in redox biology and medicine
Redox Biology · 2015 · Q1 · SJR 4.00 · FWCI 60.40 · 2,926 citations
The concept of 'oxidative stress,' formulated in 1985, has become a widely used term in biology and medicine, with over 138,000 PubMed entries by 2015.
Applications of Palladium-Catalyzed C–N Cross-Coupling Reactions
Chemical Reviews · 2016 · Q1 · SJR 16.00 · FWCI 182.33 · 2,905 citations
Palladium-catalyzed C-N cross-coupling reactions are now essential for synthesizing anilines and derivatives, driven by the development of versatile catalysts and user-friendly conditions.
Cu and Cu-Based Nanoparticles: Synthesis and Applications in Catalysis
Chemical Reviews · 2016 · Q1 · SJR 16.00 · FWCI 200.75 · 2,890 citations
This review details the synthesis and diverse catalytic applications of copper (Cu) and Cu-based nanoparticles, highlighting their earth-abundant nature and tunable properties.
Ruthenium(II)-Catalyzed C–H Bond Activation and Functionalization
Chemical Reviews · 2012 · Q1 · SJR 16.00 · FWCI 123.33 · 2,723 citations
This review consolidates recent advancements in ruthenium(II)-catalyzed C–H bond activation and functionalization, highlighting its versatility in organic synthesis.
Dual Catalysis Strategies in Photochemical Synthesis
Chemical Reviews · 2016 · Q1 · SJR 16.00 · FWCI 214.50 · 2,686 citations
This review summarizes dual-catalyst strategies that combine photocatalysis with other catalytic systems to achieve novel bond constructions in organic synthesis.
Solar Synthesis: Prospects in Visible Light Photocatalysis
Science · 2014 · Q1 · SJR 10.00 · FWCI 105.56 · 2,574 citations
Transition metal chromophores, previously used for solar energy conversion, can now harness visible light for organic synthesis, overcoming the limitations of UV-only activation.
Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design
Journal of Medicinal Chemistry · 2018 · Q1 · SJR 1.00 · FWCI 82.30 · 2,565 citations
Fluorine's unique electronic properties and small size make it a versatile bioisostere, enabling substitution for various atoms and functional groups to enhance drug properties like potency and metabolism.
Atom Transfer Radical Polymerization (ATRP): Current Status and Future Perspectives
Macromolecules · 2012 · Q1 · SJR 1.00 · FWCI 106.81 · 2,550 citations
Atom Transfer Radical Polymerization (ATRP) has advanced significantly, with current research focusing on mechanistic understanding, synthetic development, and creating novel polymer architectures and hybrid materials.
Recently added
Taming the Flexible Eight‐Membered Ring: Enantioselective Synthesis of Inherently Chiral Dibenzo[ a , e ]cyclooctatetraenes Enabled by Pd‐Catalyzed Suzuki–Miyaura Cross‐Coupling
Angewandte Chemie International Edition · 2026 · Q1 · SJR 5.00
A new Pd-catalyzed asymmetric Suzuki-Miyaura coupling method enables the efficient synthesis of inherently chiral dibenzo[a,e]cyclooctatetraene (dbCOT) ligands with up to 98% enantiomeric excess (ee).
Chiral Rh Diene NHC Complexes and Their Application in Rh-Catalyzed Cycloisomerization of Enynes
Organometallics · 2026 · Q2
A cationic Rh complex, [Rh(L1)(ICy)]SbF6, shows improved activity and selectivity in 1,6-enyne cycloisomerization compared to other Rh diene NHC catalysts, attributed to reduced deactivation.
Asymmetric Copper-Catalyzed Propargylation of 5-Aminopyrazoles with Propargylic Acetates
The Journal of Organic Chemistry · 2026 · Q2
A new asymmetric copper-catalyzed reaction enables the propargylation of 5-aminopyrazoles using propargylic acetates, yielding chiral products with up to 99:1 enantiomeric ratio (er).
Copper-Catalyzed 1,3-Propargyl Shift: Development of an Anionic Rearrangement of ortho -Metalated Aryl Propargyl Ethers
JACS Au · 2026 · Q1 · SJR 2.00
A new copper-catalyzed anionic rearrangement allows propargyl ethers to shift a propargyl group from oxygen to an ortho-carbon on an aryl ring, creating hard-to-synthesize phenol derivatives.
MALDI-TOF Mass Spectrometric Characterization of Polyacrylamide Multiblock Copolymers Reveals Structure–Property Relationships
ACS Omega · 2026 · Q1
A new method using MALDI-TOF MS precisely characterized novel polyacrylamide multiblock copolymers, revealing a strong correlation (r=0.983) between designed and actual molecular architecture and demonstrating tunable thermoresponsive behavior.
Enantioselective Synthesis of Spiropyrrolidines by Synergistic Catalysis
The Journal of Organic Chemistry · 2026 · Q2
A new method uses a combination of chiral phosphoric acid and palladium catalysts to create complex spiropyrrolidines with up to 99% enantiomeric excess.
Stereoselective Gateway to Decorated Chloro-1,3-butadienes from Allenols via Deoxygenative 1,2-Bond Migration
The Journal of Organic Chemistry · 2026 · Q2
A new strategy synthesizes E-2-chloro-1,3-butadienes from allenols via deoxygenative 1,2-bond migration, offering moderate-to-good yields and scalability.
Achiral Additives Modulated Helicity and Supramolecular Fibrillation Assembly of Helical Dendronized Poly(phenylacetylene)s through Enhanced Radial Amphiphilicity †
Chinese Journal of Chemistry · 2026 · Q1 · SJR 1.00
Achiral aromatic additives (benzoic acid, phenol, aniline) induce long helical fibers and double helices from thermoresponsive dendronized poly(phenylacetylene)s in water, contrasting with typical micelle formation.
Journals in this field
The journals that publish most of this field’s papers. Quartile (Q1–Q4), SJR and h-index are from SCImago Journal Rank; “in this field” is how many of the journal’s pooled papers belong here. What is a Q1 journal? · What is the h-index?
| Journal | Quartile | SJR | h-index | In this field | Summaries |
|---|---|---|---|---|---|
| Chemical Reviews | Q1 | 16.00 | 905 | 33 | 124 |
| Angewandte Chemie - International Edition | Q1 | 5.00 | 697 | 14 | 49 |
| Chemical Society Reviews | Q1 | 11.00 | 709 | 11 | 90 |
| Organic Letters | Q1 | 1.00 | 268 | 6 | 11 |
| Journal of Organic Chemistry | Q2 | — | 256 | 6 | 12 |
| Science | Q1 | 10.00 | 1433 | 3 | 268 |
| Accounts of Chemical Research | Q1 | 5.00 | 495 | 3 | 19 |
| Journal of Medicinal Chemistry | Q1 | 1.00 | 329 | 2 | 11 |
Every journal in Organic Chemistry (Q1–Q4) →
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