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Chemical Society Reviews· 2012Q1· Review

Far-red to near infrared analyte-responsive fluorescent probes based on organic fluorophore platforms for fluorescence imaging

Lin Yuan, Weiying Lin, Kaibo Zheng, Longwei He et al.

Short summary

This review highlights advances in far-red to NIR fluorescent probes for in vivo bioimaging, classifying them by organic dye platforms like cyanines, rhodamine analogues, BODIPYs, and squaraines.

AI-generated from the title and abstract; the full text is not read.

Key points

  • Far-red to NIR fluorescent probes offer advantages for in vivo bioimaging.
  • Key advantages include minimal photo-damage, deep tissue penetration, and reduced background auto-fluorescence.
  • Probes are classified based on their organic dye platforms.
  • Major platforms discussed are cyanines, rhodamine analogues, BODIPYs, and squaraines.

AI-generated from the title and abstract; the full text is not read.

Abstract

The long wavelength (far-red to NIR) analyte-responsive fluorescent probes are advantageous for in vivo bioimaging because of minimum photo-damage to biological samples, deep tissue penetration, and minimum interference from background auto-fluorescence by biomolecules in the living systems. Thus, great interest in the development of new long wavelength analyte-responsive fluorescent probes has emerged in recent years. This review highlights the advances in the development of far-red to NIR fluorescent probes since 2000, and the probes are classified according to their organic dye platforms into various categories, including cyanines, rhodamine analogues, BODIPYs, squaraines, and other types (240 references).

The authors' abstract, as published at the source. Chemical Society Reviews, 2012 · DOI ↗

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Field: Spectroscopy

SpectroscopyChemistry