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PROTEOMICS· 2012Q1

Comet: An open‐source <scp>MS</scp> / <scp>MS</scp> sequence database search tool

Jimmy K. Eng, Tahmina A. Jahan, Michael R. Hoopmann

Short summary

Comet is a new, open-source MS/MS sequence database search engine for proteomics research, offering a free alternative to existing commercial and open-source tools.

AI-generated from the title and abstract; the full text is not read.

Key points

  • Comet is a newly introduced MS/MS sequence database search engine.
  • The tool is open-source and freely available.
  • It is designed for peptide and protein identification in proteomics research.
  • Comet is based on a long-standing, widely-used sequence database search tool.

AI-generated from the title and abstract; the full text is not read.

Abstract

Proteomics research routinely involves identifying peptides and proteins via MS/MS sequence database search. Thus the database search engine is an integral tool in many proteomics research groups. Here, we introduce the Comet search engine to the existing landscape of commercial and open-source database search tools. Comet is open source, freely available, and based on one of the original sequence database search tools that has been widely used for many years.

The authors' abstract, as published at the source. PROTEOMICS, 2012 · DOI ↗

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Field: Spectroscopy

SpectroscopyChemistry