Chemical Reviews· 2019Q1· Review
Coumarin-Based Small-Molecule Fluorescent Chemosensors
- 1,278citations
- Q1SCImago
- 2019year
Short summary
Coumarin derivatives are increasingly used as fluorescent chemosensors due to their biocompatibility, strong fluorescence, and structural flexibility.
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Key points
- Coumarin derivatives are widely found in nature and synthesized by chemists.
- The coumarin scaffold offers excellent biocompatibility, strong fluorescence, and structural flexibility.
- These properties make coumarins suitable for designing small-molecule fluorescent chemosensors.
- Applications span molecular recognition, imaging, and bio/medical sciences.
- The review covers progress in coumarin-based chemosensors from 2012-2018.
AI-generated from the title and abstract; the full text is not read.
Abstract
-chromen-2-one motif, as it is known according to IUPAC nomenclature. Coumarin derivatives are widely found in nature, especially in plants and are constituents of several essential oils. Up to now, thousands of coumarin derivatives have been isolated from nature or produced by chemists. More recently, the coumarin platform has been widely adopted in the design of small-molecule fluorescent chemosensors because of its excellent biocompatibility, strong and stable fluorescence emission, and good structural flexibility. This scaffold has found wide applications in the development of fluorescent chemosensors in the fields of molecular recognition, molecular imaging, bioorganic chemistry, analytical chemistry, materials chemistry, as well as in the biology and medical science communities. This review focuses on the important progress of coumarin-based small-molecule fluorescent chemosensors during the period of 2012-2018. This comprehensive and critical review may facilitate the development of more powerful fluorescent chemosensors for broad and exciting applications in the future.
The authors' abstract, as published at the source. Chemical Reviews, 2019 · DOI ↗
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Field: Spectroscopy
SpectroscopyChemistry