Chemical Society Reviews· 2020Q1· Review
Förster resonance energy transfer (FRET)-based small-molecule sensors and imaging agents
- 995citations
- Q1SCImago
- 2020year
Short summary
Recent advances in constructing and applying FRET-based small-molecule fluorescent probes offer advantages like large Stokes shifts, ratiometric sensing, and multi-analyte responsiveness.
AI-generated from the title and abstract; the full text is not read.
Key points
- FRET-based fluorescent probes offer advantages like large Stokes shifts and ratiometric sensing.
- These probes can be designed for dual/multi-analyte responsive systems.
- Applications include detection and imaging of cations, anions, small neutral molecules, and biomacromolecules.
- The review covers the construction and application of these probes, focusing on dye combinations.
AI-generated from the title and abstract; the full text is not read.
Abstract
In this tutorial review, we will explore recent advances in the construction and application of Förster resonance energy transfer (FRET)-based small-molecule fluorescent probes. The advantages of FRET-based fluorescent probes include: a large Stokes shift, ratiometric sensing and dual/multi-analyte responsive systems. We discuss the underlying energy donor-acceptor dye combinations and emphasise their applications for the detection or imaging of cations, anions, small neutral molecules, biomacromolecules, cellular microenvionments and dual/multi-analyte responsive systems.
The authors' abstract, as published at the source. Chemical Society Reviews, 2020 · DOI ↗
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Field: Spectroscopy
SpectroscopyChemistry