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Environmental Microbiome· 2026Q1

Machine learning-based rescoring with MS²Rescore boosts peptide identification and taxonomic specificity in metaproteomics

Xuxa Malliet, Arthur Declercq, Ralf Gabriels, Tanja Holstein et al.

Short summary

MS²Rescore, a machine learning tool, significantly increases peptide identification rates (outperforming Sage) and lowers false discovery rates to 0.1% in metaproteomics, especially in complex environments like soil.

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Field: Spectroscopy

SpectroscopyChemistry