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Scientific Reports· 2026Q1

Carbonylation-driven oligomerization causes protein discoloration as a potential mechanism of skin tone alteration

Min Fu, Xiangyan Shi, Liwei Zhang, Mengyang Xu et al.

Short summary

Protein carbonylation drives the formation of cross-linked oligomers, causing visible yellowness in skin, a finding that could inform dermatological interventions for age-related skin tone changes.

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Field: Dermatology

DermatologyMedicine