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Cancers· 2026Q1· Review

ELN vs. IPSS-M in MDS/AML: Which Prognostic System Should Guide Clinical Decision-Making?

Maria Liga, A. N. Georgopoulou, Dimitrios Tsokanas, Alexandros Spyridonidis et al.

Short summary

IPSS-M is the preferred framework for baseline prognostic assessment of MDS/AML, showing preserved prognostic discrimination, while direct application of ELN 2022 results in adverse-risk compression and limited discrimination.

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Field: Hematology

HematologyMedicine