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Biomedicines· 2026Q1

Dynamic CD4+ T Cell Genetics Identifies Candidate Therapeutic Targets for Allergic Rhinitis: Mendelian Randomization with Exploratory Single-Cell Contextualization

Wei Gu, Jinglei Li, Chuan Liu, Chuan Chen et al.

Short summary

A Mendelian randomization analysis of dynamic CD4+ T cell gene expression identified 9 candidate genes influencing allergic rhinitis susceptibility, with SLC25A46 and TLR1 prioritized for therapeutic targeting.

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Field: Immunology and Allergy

Immunology and AllergyMedicine