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European Journal of Ophthalmology· 2026Q2

MALT lymphoma mimicking IgG4-related disease

Chun-Hsiang Chang, Chun‐Chieh Lai

Short summary

A 75-year-old man with eye fullness, proptosis, and enlarged lacrimal glands, initially suspected of IgG4-related disease due to elevated serum IgG4, was diagnosed with MALT lymphoma via lacrimal gland biopsy.

AI-generated from the title and abstract; the full text is not read.

Key points

  • Patient presented with symptoms mimicking IgG4-related disease, including eye fullness, proptosis, and lacrimal gland enlargement.
  • Elevated serum IgG4 levels initially supported the diagnosis of IgG4-related disease.
  • Lacrimal gland biopsy revealed MALT lymphoma, not IgG4-related disease.
  • Histopathological confirmation is crucial for distinguishing between MALT lymphoma and IgG4-related disease due to similar clinical features.

AI-generated from the title and abstract; the full text is not read.

Abstract

A 75-year-old man presented with left eye fullness, proptosis, and bilateral lacrimal gland enlargement with elevated serum IgG4 levels, initially suggesting IgG4-related disease. However, lacrimal gland biopsy revealed MALT lymphoma. This case highlights the overlapping clinical features of IgG4-related disease and lymphoma and emphasizes the importance of histopathological confirmation before initiating treatment.

The authors' abstract, as published at the source. European Journal of Ophthalmology, 2026 · DOI ↗

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Field: Rheumatology

RheumatologyMedicine