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JAMA· 2015Q1· Clinical trial

Transfusion of Plasma, Platelets, and Red Blood Cells in a 1:1:1 vs a 1:1:2 Ratio and Mortality in Patients With Severe Trauma

John B. Holcomb, Barbara C. Tilley, Sarah Baraniuk, Erin E. Fox et al.

Short summary

A large trial found that transfusing severely injured trauma patients with plasma, platelets, and red blood cells in a 1:1:1 ratio did not significantly reduce overall 24-hour or 30-day mortality compared to a 1:1:2 ratio.

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Field: Critical Care and Intensive Care Medicine

Critical Care and Intensive Care MedicineMedicine