Cell Transplantation· 2018Q1· Review
Fighting against Skin Aging
- 731citations
- Q1SCImago
- 2018year
Short summary
This review summarizes changes in skin aging, molecular mechanisms, and treatment strategies for preventing or reversing skin aging.
AI-generated from the title and abstract; the full text is not read.
Key points
- Skin aging involves cellular and extracellular matrix changes, including collagen and elastin degradation.
- Both intrinsic and extrinsic factors contribute to skin aging.
- Research is advancing our understanding of the molecular mechanisms behind skin aging.
- Treatment strategies focus on preventing or reversing the signs of skin aging.
AI-generated from the title and abstract; the full text is not read.
Abstract
As the most voluminous organ of the body that is exposed to the outer environment, the skin suffers from both intrinsic and extrinsic aging factors. Skin aging is characterized by features such as wrinkling, loss of elasticity, laxity, and rough-textured appearance. This aging process is accompanied with phenotypic changes in cutaneous cells as well as structural and functional changes in extracellular matrix components such as collagens and elastin. In this review, we summarize these changes in skin aging, research advances of the molecular mechanisms leading to these changes, and the treatment strategies aimed at preventing or reversing skin aging.
The authors' abstract, as published at the source. Cell Transplantation, 2018 · DOI ↗
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Field: Dermatology
DermatologyMedicine