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Dermatologic Surgery· 2016Q2

Keloids and Hypertrophic Scars: Pathophysiology, Classification, and Treatment

Brian Berman, Andrea D. Maderal, Brian A. Raphael

Short summary

Keloid and hypertrophic scars result from dysregulated wound healing with excessive collagen formation, causing cosmetic and functional issues. While their exact pathophysiology is unknown, cytokines like IL-6, IL-8, and IL-10, and growth factors such as TGF-beta and PDGF are implicated.

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Field: Dermatology

DermatologyMedicine