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Cell· 2014Q1

Integrated Genomic Characterization of Papillary Thyroid Carcinoma

Nishant Agrawal, Rehan Akbani, Bülent Arman Aksoy, Adrian Ally et al.

Short summary

Genomic analysis of 496 papillary thyroid carcinomas (PTCs) identified new driver alterations (EIF1AX, PPM1D, CHEK2, and gene fusions), reducing the proportion of PTC cases with unknown drivers from 25% to 3.5%.

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Field: Endocrinology, Diabetes and Metabolism

Endocrinology, Diabetes and MetabolismMedicine