Physiology· 2013Q1· Review
Exercise is the Real Polypill
- 784citations
- Q1SCImago
- 2013year
Short summary
Regular exercise offers comparable or superior cardiovascular disease prevention and treatment benefits to the proposed "polypill" drug strategy, acting as a drug-free, evolutionarily shaped intervention.
AI-generated from the title and abstract; the full text is not read.
Key points
- Exercise provides comparable or superior cardiovascular benefits to polypill strategies.
- Exercise is a drug-free intervention shaped by human evolution.
- Compared to pharmaceuticals, exercise is low-cost and has minimal adverse effects.
- The paper summarizes epidemiological evidence and biological mediators of exercise benefits.
AI-generated from the title and abstract; the full text is not read.
Abstract
The concept of a "polypill" is receiving growing attention to prevent cardiovascular disease. Yet similar if not overall higher benefits are achievable with regular exercise, a drug-free intervention for which our genome has been haped over evolution. Compared with drugs, exercise is available at low cost and relatively free of adverse effects. We summarize epidemiological evidence on the preventive/therapeutic benefits of exercise and on the main biological mediators involved.
The authors' abstract, as published at the source. Physiology, 2013 · DOI ↗
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Field: Family Practice
Family PracticeMedicine