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Patient Preference and Adherence· 2013Q1· Review

Definitions, variants, and causes of nonadherence with medication: a challenge for tailored interventions

Jacqueline G. Hugtenburg, Marcia Vervloet, Liset van Dijk, Lonneke Timmers et al.

Short summary

Tailored interventions, such as electronic pill boxes with SMS reminders and personalized internet or counseling programs, show promise for improving medication adherence by addressing specific patient needs and causes of nonadherence.

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Key points

  • Nonadherence to medication is a multidimensional problem with patient, treatment, and healthcare provider-related causes.
  • Most interventions to improve adherence have modest effects and are not tailored to individual patient needs.
  • Tailored interventions, including electronic pill boxes with SMS reminders and personalized counseling, show promise for improving adherence.
  • Electronic pill boxes with SMS reminders have increased refill adherence in diabetic patients with suboptimal adherence.
  • Long-term health effects of various tailored interventions are not yet available.

AI-generated from the title and abstract; the full text is not read.

Abstract

BACKGROUND: Nonadherence with medication is a complex and multidimensional health care problem. The causes may be related to the patient, treatment, and/or health care provider. As a consequence, substantial numbers of patients do not benefit optimally from pharmacotherapy, resulting in increased morbidity and mortality as well as increased societal costs. Several interventions may contribute to improved adherence. However, most interventions have only a modest effect. Thus, despite the many efforts made, there has been little progress made as yet in tackling the problem of nonadherence. METHODS: This paper summarizes the definitions and taxonomy of adherence with medication, as well as types and causes of nonadherence. In addition, interventions aimed at improvement of adherence are discussed. CONCLUSION: There is not just one solution for the nonadherence problem that fits all patients. Most interventions to improve adherence are aimed at all patients regardless of whether they are adherent or not. Recently, a number of tailored interventions have been described in the literature. Modern techniques are useful. Electronic pill boxes combined with Short Message Service reminders are specifically designed to improve unintentional adherence and have resulted in an increase in refill adherence in diabetic patients with suboptimal adherence. Tailored Internet interventions are a possibility for influencing patient drug-taking behavior and show promising results. Tailored counseling interventions targeted at the underlying causes of nonadherence seem an attractive method for supporting patients with their use of drugs. However, despite the plausible theoretical framework, data on long-term health effects of the various interventions are not available. To improve adherence effectively, there is a need for a tailored approach based on the type and cause of nonadherence and the specific needs of the patient.

The authors' abstract, as published at the source. Patient Preference and Adherence, 2013 · DOI ↗

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Field: Family Practice

Family PracticeMedicine