International Journal of Surgical Pathology· 2026Q2
Ameloblastoma With Glandular Differentiation
- 0citations
- Q2SCImago
- 2026year
Short summary
A KRASG12R-mutated ameloblastoma in a 72-year-old male exhibited mucinous glandular differentiation, a subtype not recognized by the WHO.
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Key points
- A mandibular ameloblastoma in a 72-year-old male displayed mucinous glandular differentiation.
- The tumor harbored a KRASG12R mutation.
- This case is the 15th reported instance of ameloblastoma with a mucinous component.
- It is the first report to provide comprehensive analysis supporting glandular differentiation.
AI-generated from the title and abstract; the full text is not read.
Abstract
Ameloblastoma with mucinous and/or glandular differentiation is exceedingly rare and not currently recognized by the World Health Organization (WHO) as a morphologic subtype. We report a KRASG12R -mutated mandibular ameloblastoma with mucinous glandular differentiation in a 72-year-old male patient, with detailed radiologic, histomorphologic, immunohistochemical and molecular findings. To our knowledge, this is the 15 th case report in literature of human ameloblastoma with a mucinous component, and the first to provide comprehensive analysis to support glandular differentiation.
The authors' abstract, as published at the source. International Journal of Surgical Pathology, 2026 · DOI ↗
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Field: Oral Surgery
Oral SurgeryDentistry