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JAMA Internal Medicine· 2016Q1

Proton Pump Inhibitor Use and the Risk of Chronic Kidney Disease

Benjamin Lazarus, Yuan Chen, F. Perry Wilson, Yingying Sang et al.

Short summary

Proton pump inhibitor (PPI) use is associated with a 35-50% increased risk of developing chronic kidney disease (CKD), with twice-daily dosing showing a higher risk than once-daily.

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Field: Gastroenterology

GastroenterologyMedicine