The American Journal of Gastroenterology· 2014Q1

American College of Gastroenterology Monograph on the Management of Irritable Bowel Syndrome and Chronic Idiopathic Constipation

Alexander C. Ford, Paul Moayyedi, Brian E. Lacy, Anthony Lembo et al.

Short summary

A systematic review of 52 trials (n=11,790) found that linaclotide improved global IBS symptoms by 15% and abdominal pain by 30% compared to placebo.

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