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Gut· 2012Q1

The brain–gut pathway in functional gastrointestinal disorders is bidirectional: a 12-year prospective population-based study

Natasha A. Koloski, Michael Jones, Jamshid S. Kalantar, Martin Weltman et al.

Short summary

A 12-year prospective study (n=1002) found that anxiety predicts new onset functional gastrointestinal disorders (FGIDs), and FGIDs predict increased anxiety and depression over time, indicating a bidirectional brain-gut pathway.

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Field: Gastroenterology

GastroenterologyMedicine