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New England Journal of Medicine· 2017Q1· Clinical trial

Nusinersen versus Sham Control in Infantile-Onset Spinal Muscular Atrophy

Richard S. Finkel, Eugenio Mercuri, Basil T. Darras, Anne M. Connolly et al.

Short summary

In infants with spinal muscular atrophy, nusinersen treatment significantly improved motor function and survival compared to a sham control, with 51% achieving motor milestones versus 0% in the control group.

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Field: Genetics

GeneticsMedicine