New England Journal of Medicine· 2017Q1
Sickle Cell Disease
- 1,332citations
- Q1SCImago
- 2017year
Short summary
Sickle cell disease, caused by a single DNA base alteration, is increasingly understood to be influenced by genetic, behavioral, and environmental factors, paving the way for new interventions.
AI-generated from the title and abstract; the full text is not read.
Key points
- Sickle cell disease originates from a single DNA base change.
- Clinical manifestations are influenced by multiple genes.
- Behavioral and environmental factors also play a role in disease presentation.
- Recent findings signal accelerated development of disease-altering interventions.
AI-generated from the title and abstract; the full text is not read.
Abstract
Sickle cell disease is caused by an alteration in a single DNA base, but its clinical manifestations are influenced by other genes and behavioral and environmental factors. Recent findings may indicate an acceleration in the discovery of interventions that alter the disease course.
The authors' abstract, as published at the source. New England Journal of Medicine, 2017 · DOI ↗
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Field: Genetics (Medicine)
GeneticsMedicine