mBio· 2016Q1

Resveratrol Attenuates Trimethylamine- <i>N</i> -Oxide (TMAO)-Induced Atherosclerosis by Regulating TMAO Synthesis and Bile Acid Metabolism via Remodeling of the Gut Microbiota

Mingliang Chen, Long Yi, Yong Zhang, Xi Zhou et al.

761citations
Q1SCImago
2016year

Short summary

Resveratrol (RSV) attenuates trimethylamine-N-oxide (TMAO)-induced atherosclerosis in mice by remodeling gut microbiota, decreasing TMAO production, and increasing bile acid (BA) neosynthesis via the FXR-FGF15 axis.

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Field: Geriatrics and Gerontology

Geriatrics and GerontologyMedicine