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New England Journal of Medicine· 2016Q1

Genomic Classification and Prognosis in Acute Myeloid Leukemia

Elli Papaemmanuil, Moritz Gerstung, Lars Bullinger, Verena I. Gaidzik et al.

Short summary

A large-scale genomic analysis of 1540 acute myeloid leukemia (AML) patients has identified 11 distinct molecular subgroups, revealing that combinations of gene mutations, rather than single mutations, significantly impact disease progression and patient outcomes.

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Field: Hematology

HematologyMedicine