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Allergy· 2014Q1· Review

Anaphylaxis: guidelines from the European Academy of Allergy and Clinical Immunology

Antonella Muraro, Graham Roberts, Margitta Worm, Maria Beatrice Bilò et al.

Short summary

New guidelines from the European Academy of Allergy and Clinical Immunology (EAACI) provide evidence-based recommendations for recognizing, assessing risk, and managing anaphylaxis, a potentially life-threatening emergency.

AI-generated from the title and abstract; the full text is not read.

Key points

  • Anaphylaxis requires prompt recognition and management by all healthcare professionals.
  • Intramuscular adrenaline is the primary treatment for anaphylaxis.
  • Guidelines cover acute management, trigger removal, patient positioning, and oxygen/fluid administration.
  • Essential discharge planning includes emergency action plans and adrenaline auto-injector education.
  • Specialist follow-up is crucial for trigger identification and personalized prevention strategies.

AI-generated from the title and abstract; the full text is not read.

Abstract

Anaphylaxis is a clinical emergency, and all healthcare professionals should be familiar with its recognition and acute and ongoing management. These guidelines have been prepared by the European Academy of Allergy and Clinical Immunology (EAACI) Taskforce on Anaphylaxis. They aim to provide evidence-based recommendations for the recognition, risk factor assessment, and the management of patients who are at risk of, are experiencing, or have experienced anaphylaxis. While the primary audience is allergists, these guidelines are also relevant to all other healthcare professionals. The development of these guidelines has been underpinned by two systematic reviews of the literature, both on the epidemiology and on clinical management of anaphylaxis. Anaphylaxis is a potentially life-threatening condition whose clinical diagnosis is based on recognition of a constellation of presenting features. First-line treatment for anaphylaxis is intramuscular adrenaline. Useful second-line interventions may include removing the trigger where possible, calling for help, correct positioning of the patient, high-flow oxygen, intravenous fluids, inhaled short-acting bronchodilators, and nebulized adrenaline. Discharge arrangements should involve an assessment of the risk of further reactions, a management plan with an anaphylaxis emergency action plan, and, where appropriate, prescribing an adrenaline auto-injector. If an adrenaline auto-injector is prescribed, education on when and how to use the device should be provided. Specialist follow-up is essential to investigate possible triggers, to perform a comprehensive risk assessment, and to prevent future episodes by developing personalized risk reduction strategies including, where possible, commencing allergen immunotherapy. Training for the patient and all caregivers is essential. There are still many gaps in the evidence base for anaphylaxis.

The authors' abstract, as published at the source. Allergy, 2014 · DOI ↗

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Field: Immunology and Allergy

Immunology and AllergyMedicine