Journal of Glaucoma· 2014Q1
Biology of the Extracellular Matrix
- 797citations
- Q1SCImago
- 2014year
Short summary
The extracellular matrix (ECM) is a complex, dynamic network of macromolecules that provides structural integrity to tissues and regulates fundamental cellular behaviors.
AI-generated from the title and abstract; the full text is not read.
Key points
- ECM components form a stable composite, providing structural integrity and mechanical properties to tissues.
- ECM serves as a reservoir for growth factors and bioactive molecules.
- ECM dynamically controls fundamental cell behaviors like proliferation, adhesion, migration, and differentiation.
AI-generated from the title and abstract; the full text is not read.
Abstract
The extracellular matrix (ECM) is an intricate network composed of an array of multidomain macromolecules organized in a cell/tissue-specific manner. Components of the ECM link together to form a structurally stable composite, contributing to the mechanical properties of tissues. The ECM is also a reservoir of growth factors and bioactive molecules. It is a highly dynamic entity that is of vital importance, determining and controlling the most fundamental behaviors and characteristics of cells such as proliferation, adhesion, migration, polarity, differentiation, and apoptosis.
The authors' abstract, as published at the source. Journal of Glaucoma, 2014 · DOI ↗
Continue with a free account
Ask the paper: 3 free questions a day about this paper; save it, get its citation, new summaries every day for your field. Takeaways are Premium.
Continue free on the webSign in with Google or Apple; no card needed. You come back to this paper.
On your phone:
Field: Immunology and Allergy
Immunology and AllergyMedicine