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Science· 2020Q1

Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation

Daniel Wrapp, Nianshuang Wang, Kizzmekia S. Corbett, Jory A. Goldsmith et al.

Short summary

Researchers determined the 3.5-angstrom cryo-EM structure of the 2019-nCoV spike protein in its prefusion state, revealing a predominant conformation with one receptor-binding domain accessible for interaction.

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Field: Infectious Diseases

Infectious DiseasesMedicine