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Cardiovascular Research· 2018Q1· Review

Role of smooth muscle cells in vascular calcification: implications in atherosclerosis and arterial stiffness

Andrew Durham, Mei Y. Speer, Marta Scatena, Cecilia M. Giachelli et al.

Short summary

Vascular smooth muscle cells (VSMCs) actively drive vascular calcification through multiple phenotypes beyond contractile or synthetic, including calcific, adipogenic, and macrophagic, with implications for atherosclerosis and arterial stiffness.

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Field: Nephrology

NephrologyMedicine