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Journal of Clinical Investigation· 2014Q1

Molecular mechanisms of diabetic kidney disease

Kimberly J. Reidy, Hyun Mi Kang, Thomas H. Hostetter, Katalin Suszták

Short summary

Diabetic kidney disease (DKD) initiation is driven by hyperglycemia-induced metabolic alterations and mitochondrial dysfunction, while angiotensin system inhibition is key to slowing progression.

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Field: Nephrology

NephrologyMedicine