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New England Journal of Medicine· 2017Q1

Amyotrophic Lateral Sclerosis

Robert H. Brown, Ammar Al‐Chalabi

Short summary

Despite advances in understanding ALS genetics and pathophysiology, no intervention has yet altered the disease's course.

AI-generated from the title and abstract; the full text is not read.

Key points

  • Understanding of ALS genetics and pathophysiology has advanced.
  • No successful intervention has been developed to alter the disease's course.
  • ALS is a crippling motor neuron disease.

AI-generated from the title and abstract; the full text is not read.

Abstract

Progress has been made in understanding the genetic defects and the pathophysiology of this crippling motor neuron disease (commonly called Lou Gehrig’s disease). However, this information has not yet led to a successful intervention that alters the course of the disease.

The authors' abstract, as published at the source. New England Journal of Medicine, 2017 · DOI ↗

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Field: Neurology (Medicine)

NeurologyMedicine