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New England Journal of Medicine· 2016Q1

Pembrolizumab versus Chemotherapy for PD-L1–Positive Non–Small-Cell Lung Cancer

Martin Reck, Delvys Rodríguez‐Abreu, Andrew Robinson, Rina Hui et al.

Short summary

Pembrolizumab significantly improved progression-free survival (10.3 vs. 6.0 months) and overall survival (80.2% at 6 months vs. 72.4%) in patients with advanced non-small-cell lung cancer (NSCLC) expressing PD-L1 on at least 50% of tumor cells, compared to chemotherapy.

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Field: Oncology

OncologyMedicine