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New England Journal of Medicine· 2015Q1

Pembrolizumab versus Ipilimumab in Advanced Melanoma

Caroline Robert, Jacob Schachter, Georgina V. Long, Ana Arance et al.

Short summary

Pembrolizumab significantly improved progression-free survival (47.3% vs. 26.5% at 6 months) and overall survival (74.1% vs. 58.2% at 12 months) compared to ipilimumab in advanced melanoma patients, with a lower rate of severe adverse events (10.1-13.3% vs. 19.9%).

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Field: Oncology

OncologyMedicine