Journal of Medical Virology· 2020Q1
Evaluation of coronavirus in tears and conjunctival secretions of patients with SARS‐CoV‐2 infection
- 1,149citations
- Q1SCImago
- 2020year
Short summary
SARS-CoV-2 RNA was detected in tear and conjunctival secretions from one out of 30 patients with COVID-19, specifically in the single patient who presented with conjunctivitis.
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Key points
- SARS-CoV-2 RNA was tested in tears and conjunctival secretions of 30 COVID-19 patients.
- One patient with conjunctivitis yielded positive RT-PCR results in eye secretions.
- All other 58 samples from patients without conjunctivitis were negative.
- The study was a prospective interventional case series.
AI-generated from the title and abstract; the full text is not read.
Abstract
OBJECTIVE: This study aimed to assess the presence of novel coronavirus in tears and conjunctival secretions of SARS-CoV-2-infected patients. METHODS: A prospective interventional case series study was performed, and 30 confirmed novel coronavirus pneumonia (NCP) patients were selected at the First Affiliated Hospital of Zhejiang University from 26 January 2020 to 9 February 2020. At an interval of 2 to 3 days, tear and conjunctival secretions were collected twice with disposable sampling swabs for reverse-transcription polymerase chain reaction (RT-PCR) assay. RESULTS: Twenty-one common-type and nine severe-type NCP patients were enrolled. Two samples of tear and conjunctival secretions were obtained from the only one patient with conjunctivitis yielded positive RT-PCR results. Fifty-eight samples from other patents were all negative. CONCLUSION: We speculate that SARS-CoV-2 may be detected in the tears and conjunctival secretions in NCP patients with conjunctivitis.
The authors' abstract, as published at the source. Journal of Medical Virology, 2020 · DOI ↗
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Field: Ophthalmology
OphthalmologyMedicine