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Proceedings of the National Academy of Sciences· 2016Q1

Retinal neurodegeneration may precede microvascular changes characteristic of diabetic retinopathy in diabetes mellitus

Elliott H. Sohn, Hille W. van Dijk, Chunhua Jiao, Pauline H. B. Kok et al.

Short summary

In people with diabetes and no to minimal diabetic retinopathy (DR), inner retinal neurodegeneration, evidenced by progressive thinning of the nerve fiber layer (NFL) and ganglion cell (GC) layer (0.25-0.29 μm/year), was observed over 4 years via OCT, independent of key patient factors.

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Field: Ophthalmology

OphthalmologyMedicine