JAMA· 2016Q1

Effect of Subcutaneous Dupilumab on Nasal Polyp Burden in Patients With Chronic Sinusitis and Nasal Polyposis

Claus Bachert, Leda Mannent, Robert M. Naclerio, Joaquim Mullol et al.

789citations
Q1SCImago
2016year

Short summary

In adults with chronic sinusitis and nasal polyposis refractory to nasal steroids, subcutaneous dupilumab plus mometasone furoate nasal spray reduced endoscopic nasal polyp score by a mean difference of -1.6 (P < .001) compared to placebo plus nasal spray after 16 weeks.

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Field: Otorhinolaryngology

OtorhinolaryngologyMedicine