Key papers in Otorhinolaryngology
Pofolia’s corpus holds 58 papers from the Otorhinolaryngology subfield (2012–2023). The list below starts with the most cited.
Most cited
Ranked by citation count. Because citations accumulate over time, this list naturally leans towards work published a few years ago; for where the field is now, see “recently added”.
European Position Paper on Rhinosinusitis and Nasal Polyps 2020
Rhinology Journal · 2020 · Q1 · SJR 2.00 · FWCI 330.76 · 5,533 citations · Open access
This position paper provides evidence-based recommendations for the diagnosis and treatment of rhinosinusitis and nasal polyps, emphasizing the unified term 'rhinosinusitis' for concurrent nasal and sinus inflammation.
Nivolumab for Recurrent Squamous-Cell Carcinoma of the Head and Neck
New England Journal of Medicine · 2016 · Q1 · SJR 18.00 · FWCI 341.88 · 5,101 citations · Open access
Nivolumab, an anti-PD-1 antibody, significantly improved overall survival in patients with recurrent head and neck squamous-cell carcinoma after platinum chemotherapy, offering a new standard of care.
Head and neck squamous cell carcinoma
Nature Reviews Disease Primers · 2020 · Q1 · SJR 15.00 · FWCI 280.64 · 4,077 citations · Open access
Head and neck squamous cell carcinoma (HNSCC) is a group of cancers primarily linked to tobacco/alcohol (HPV-negative) or HPV infection (HPV-positive), with recent advances including immune checkpoint inhibitors like pembrolizumab and nivolumab for advanced stages.
EPOS 2012: European position paper on rhinosinusitis and nasal polyps 2012. A summary for otorhinolaryngologists
Rhinology Journal · 2012 · Q1 · SJR 2.00 · FWCI 132.54 · 2,410 citations
The EPOS 2012 update provides refined definitions for difficult-to-treat rhinosinusitis, disease control, and pediatric cases, alongside updated diagnostic and treatment guidelines based on the latest evidence.
Head and Neck Cancer
New England Journal of Medicine · 2020 · Q1 · SJR 18.00 · FWCI 178.15 · 2,086 citations
The majority of head and neck cancers (73% in the US) are now linked to HPV, shifting from traditional causes like tobacco and alcohol.
Clinical Practice Guideline: Otitis Media with Effusion (Update)
Otolaryngology · 2016 · FWCI 59.99 · 2,010 citations · Open access
New clinical practice guidelines recommend watchful waiting for 3 months for most children with otitis media with effusion (OME) and strongly advise against using steroids, antibiotics, or antihistamines for treatment.
Head and neck cancers—major changes in the American Joint Committee on cancer eighth edition cancer staging manual
CA A Cancer Journal for Clinicians · 2017 · Q1 · SJR 104.00 · FWCI 135.91 · 1,672 citations · Open access
The 8th edition of the AJCC Staging Manual for head and neck cancers introduces significant revisions, most notably a separate staging system for high-risk HPV-associated oropharyngeal cancers.
The Diagnosis and Management of Acute Otitis Media
PEDIATRICS · 2013 · Q1 · SJR 2.00 · FWCI 74.75 · 1,432 citations
This revised clinical practice guideline offers updated recommendations for primary care clinicians on diagnosing and managing acute otitis media (AOM) in children aged 6 months to 12 years.
Head and Neck Cancers, Version 2.2020, NCCN Clinical Practice Guidelines in Oncology
Journal of the National Comprehensive Cancer Network · 2020 · Q1 · SJR 5.00 · FWCI 132.05 · 1,383 citations
Updated NCCN guidelines for head and neck cancers introduce new imaging recommendations and revised systemic therapy options for very advanced disease and salivary gland tumors.
European Position Paper on Rhinosinusitis and Nasal Polyps
2014 · FWCI 209.95 · 1,334 citations · Open access
This European position paper provides evidence-based recommendations for rhinosinusitis and nasal polyp treatment, highlighting areas with strong recommendations and significant data gaps.
Worldwide Trends in Incidence Rates for Oral Cavity and Oropharyngeal Cancers
Journal of Clinical Oncology · 2013 · Q1 · SJR 4.00 · FWCI 60.56 · 1,296 citations · Open access
Oropharyngeal cancer (OPC) incidence significantly increased globally from 1983-2002, particularly in developed countries and younger men, suggesting a growing role for HPV infection.
Long-Term Results of RTOG 91-11: A Comparison of Three Nonsurgical Treatment Strategies to Preserve the Larynx in Patients With Locally Advanced Larynx Cancer
Journal of Clinical Oncology · 2012 · Q1 · SJR 4.00 · FWCI 50.86 · 1,283 citations · Open access
Adding chemotherapy to radiation therapy significantly improved larynx preservation rates in locally advanced larynx cancer patients compared to radiation alone, with concomitant chemotherapy showing superior larynx preservation over induction chemotherapy.
Epidemiology of Human Papillomavirus–Positive Head and Neck Squamous Cell Carcinoma
Journal of Clinical Oncology · 2015 · Q1 · SJR 4.00 · FWCI 59.56 · 1,241 citations
Human papillomavirus (HPV) is the primary driver behind rising rates of a specific type of head and neck cancer globally. Understanding its epidemiology is crucial for developing interventions to reverse these trends.
EPOS 2012: European position paper on rhinosinusitis and nasal polyps 2012. A summary for otorhinolaryngologists
Rhinology Journal · 2012 · Q1 · SJR 2.00 · FWCI 59.12 · 1,197 citations · Open access
This summary of the EPOS 2012 guidelines provides evidence-based recommendations for treating rhinosinusitis and nasal polyps, highlighting treatments with limited or no supporting data.
EPOS2020: A Major Step Forward
Rhinology Journal · 2020 · Q1 · SJR 2.00 · FWCI 101.36 · 1,196 citations · Open access
The EPOS2020 guideline offers updated, evidence-based recommendations and integrated care pathways for Acute and Chronic Rhinosinusitis (ARS and CRS). It addresses areas previously less covered, such as pediatric CRS and sinus surgery.
Elective versus Therapeutic Neck Dissection in Node-Negative Oral Cancer
New England Journal of Medicine · 2015 · Q1 · SJR 18.00 · FWCI 60.97 · 1,192 citations · Open access
For early-stage oral cancer patients with no lymph node involvement, performing elective neck dissection during initial surgery significantly improves overall and disease-free survival compared to waiting for relapse.
Clinical Practice Guideline (Update): Adult Sinusitis
Otolaryngology · 2015 · FWCI 72.51 · 1,162 citations · Open access
New guidelines for adult sinusitis management emphasize distinguishing bacterial from viral infections and recommend watchful waiting or antibiotics for acute bacterial rhinosinusitis. Chronic sinusitis management now includes assessing for underlying conditions and offering saline irrigation or intranasal corticosteroids for symptom relief.
Oral cavity and oropharyngeal squamous cell carcinoma—an update
CA A Cancer Journal for Clinicians · 2015 · Q1 · SJR 104.00 · FWCI 44.49 · 1,103 citations · Open access
Oropharyngeal squamous cell carcinoma (OP-SCC) incidence is rising dramatically, particularly HPV-related cases, necessitating awareness of its distinct characteristics compared to oral cavity squamous cell carcinoma (OC-SCC).
Burden of Disease Caused by Otitis Media: Systematic Review and Global Estimates
PLoS ONE · 2012 · Q1 · FWCI 5.65 · 1,091 citations · Open access
Otitis media (OM) causes 709 million acute cases annually, with over half in children under five, and 31 million chronic suppurative cases, leading to significant hearing loss and 21,000 deaths yearly.
Prevalence of Oral HPV Infection in the United States, 2009-2010
JAMA · 2012 · Q1 · SJR 5.00 · FWCI 84.22 · 1,066 citations
Oral HPV infection affects 6.9% of US adults aged 14-69, with men showing a significantly higher prevalence (10.1%) than women (3.6%).
Recently added
Epidemiology, Risk Factors, and Prevention of Head and Neck Squamous Cell Carcinoma
Medical Sciences · 2023 · Q1 · SJR 1.00 · FWCI 160.28 · 672 citations · Open access
Head and neck squamous cell carcinoma (HNSCC) is the seventh most common cancer globally, with 890,000 new cases and 450,000 deaths annually. Risk factors vary by region, including tobacco, alcohol, and areca nut in developing nations, and HPV in developed nations.
Reviewing the epidemiology of head and neck cancer: definitions, trends and risk factors
BDJ · 2022 · Q2 · FWCI 112.98 · 726 citations · Open access
Head and neck cancer incidence is rising globally, driven by oropharyngeal cancers, with mortality rates also increasing due to static survival rates.
NCCN Guidelines® Insights: Head and Neck Cancers, Version 1.2022
Journal of the National Comprehensive Cancer Network · 2022 · Q1 · SJR 5.00 · FWCI 93.15 · 532 citations
NCCN Guidelines for Head and Neck Cancers (Version 1.2022) now summarize updated recommendations for HPV-positive oropharynx cancer management and ongoing research.
Head and neck squamous cell carcinoma
Nature Reviews Disease Primers · 2020 · Q1 · SJR 15.00 · FWCI 280.64 · 4,077 citations · Open access
Head and neck squamous cell carcinoma (HNSCC) is a group of cancers primarily linked to tobacco/alcohol (HPV-negative) or HPV infection (HPV-positive), with recent advances including immune checkpoint inhibitors like pembrolizumab and nivolumab for advanced stages.
International consensus statement on allergy and rhinology: rhinosinusitis 2021
International Forum of Allergy & Rhinology · 2020 · Q1 · SJR 1.00 · FWCI 65.38 · 903 citations
The ICAR-RS-2021 updates and expands upon the previous consensus statement, introducing over 40 new topics and revising 140 existing ones concerning rhinologic disease.
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