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Science· 2017Q1

Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade

Dung T. Le, Jennifer N. Durham, Kellie N. Smith, Hao Wang et al.

Short summary

Solid tumors with mismatch repair deficiency show a high response rate to PD-1 blockade therapy, with 53% objective radiographic responses and 21% complete responses across 12 tumor types.

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Field: Pathology and Forensic Medicine

Pathology and Forensic MedicineMedicine