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Leukemia· 2022Q1· Review

The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Lymphoid Neoplasms

Rita Alaggio, Catalina Amador, Ioannis Anagnostopoulos, Ayoma D. Attygalle et al.

Short summary

The upcoming 5th edition of the WHO Classification of Haematolymphoid Tumours introduces a hierarchical system for lymphoid neoplasms, alongside revised nomenclature, diagnostic criteria, and the inclusion of new entities and germline predisposition syndromes.

AI-generated from the title and abstract; the full text is not read.

Key points

  • Adoption of a hierarchical organizational system for lymphoid neoplasms.
  • Updates to nomenclature and diagnostic criteria for existing entities.
  • Inclusion of new lymphoid neoplasm entities.
  • Integration of tumour-like lesions, mesenchymal lesions, and germline predisposition syndromes.

AI-generated from the title and abstract; the full text is not read.

Abstract

Abstract We herein present an overview of the upcoming 5 th edition of the World Health Organization Classification of Haematolymphoid Tumours focussing on lymphoid neoplasms. Myeloid and histiocytic neoplasms will be presented in a separate accompanying article. Besides listing the entities of the classification, we highlight and explain changes from the revised 4 th edition. These include reorganization of entities by a hierarchical system as is adopted throughout the 5 th edition of the WHO classification of tumours of all organ systems, modification of nomenclature for some entities, revision of diagnostic criteria or subtypes, deletion of certain entities, and introduction of new entities, as well as inclusion of tumour-like lesions, mesenchymal lesions specific to lymph node and spleen, and germline predisposition syndromes associated with the lymphoid neoplasms.

The authors' abstract, as published at the source. Leukemia, 2022 · DOI ↗

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Field: Pathology and Forensic Medicine

Pathology and Forensic MedicineMedicine