Physiological Reviews· 2015Q1· Review

Vitamin D: Metabolism, Molecular Mechanism of Action, and Pleiotropic Effects

Sylvia Christakos, Puneet Dhawan, Annemieke Verstuyf, Lieve Verlinden et al.

1,915citations
Q1SCImago
2015year

Short summary

The active form of vitamin D, 1,25(OH)2D3, directly binds to DNA via the VDR/RXR complex, regulating gene activity at distant sites, and has extraskeletal effects including cancer inhibition, cardiovascular benefits, and immunomodulation.

AI-generated from the title and abstract; the full text is not read.

TakeawaysIn the app

Key pointsIn the app

Ask the paperIn the app

The rest is in the Pofolia app

Takeaways, key points and questions to the paper; new summaries every day for your field. Free.

Get it on Google Play Download on the App Store

Field: Pathology and Forensic Medicine

Pathology and Forensic MedicineMedicine