European Neurology· 2015Q2· Review

Update on the Autoimmune Pathology of Multiple Sclerosis: B-Cells as Disease-Drivers and Therapeutic Targets

H.‐Christian von Büdingen, Arumugam Palanichamy, Klaus Lehmann‐Horn, Brady Michel et al.

1,475citations
Q2SCImago
2015year

Short summary

B-cells are key drivers of multiple sclerosis (MS) pathogenesis, and their depletion via targeted therapies, such as anti-CD20 antibodies, effectively ameliorates disease activity.

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Field: Pathology and Forensic Medicine

Pathology and Forensic MedicineMedicine