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New England Journal of Medicine· 2016Q1

Graves’ Disease

Terry J. Smith, László Hegedüs

Short summary

Graves' disease is an autoimmune disorder where antibodies mistakenly activate the thyroid's thyrotropin receptor, leading to hyperthyroidism and other life-impacting symptoms.

AI-generated from the title and abstract; the full text is not read.

Key points

  • Graves' disease is an autoimmune disorder.
  • Antibodies activate the thyrotropin receptor in the thyroid.
  • This activation leads to hyperthyroidism.
  • The disease causes somatic and psychiatric manifestations.
  • Symptoms can negatively impact quality and length of life.

AI-generated from the title and abstract; the full text is not read.

Abstract

Graves' disease is an autoimmune disorder in which the thyroid is activated by antibodies to the thyrotropin receptor. The hyperthyroidism that develops is one of many somatic and psychiatric manifestations of the disease that can affect the quality and length of life.

The authors' abstract, as published at the source. New England Journal of Medicine, 2016 · DOI ↗

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Field: Pathology and Forensic Medicine

Pathology and Forensic MedicineMedicine