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New England Journal of Medicine· 2021Q1

Diffuse Large B-Cell Lymphoma

Laurie H. Sehn, Gilles Salles

Short summary

Diffuse Large B-Cell Lymphoma (DLBCL) is an aggressive cancer representing 30% of lymphomas, with current standard chemotherapy curing approximately 65% of patients initially and an additional 20-25% with salvage therapy.

AI-generated from the title and abstract; the full text is not read.

Key points

  • DLBCL accounts for approximately 30% of all lymphoma diagnoses.
  • Standard combination chemotherapy cures about 65% of DLBCL patients initially.
  • An additional 20-25% of DLBCL patients can be cured with salvage therapy.
  • Ongoing research aims to tailor DLBCL treatments to specific genetic alterations.

AI-generated from the title and abstract; the full text is not read.

Abstract

DLBCL, an aggressive cancer, accounts for about 30% of all lymphomas. Empirical combination chemotherapy cures about 65% of patients initially, with another 20 to 25% cured with salvage therapy. Efforts are ongoing to tailor therapy to particular genetic lesions.

The authors' abstract, as published at the source. New England Journal of Medicine, 2021 · DOI ↗

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Field: Pathology and Forensic Medicine

Pathology and Forensic MedicineMedicine