Clinical Infectious Diseases· 2014Q1

DALI: Defining Antibiotic Levels in Intensive Care Unit Patients: Are Current -Lactam Antibiotic Doses Sufficient for Critically Ill Patients?

Jason A. Roberts, Sanjoy K. Paul, Murat Akova, Matteo Bassetti et al.

1,091citations
Q1SCImago
2014year

Short summary

Infections in critically ill patients are a major problem, and the DALI study found that 16% of these patients did not achieve target beta-lactam antibiotic concentrations, leading to a 32% lower likelihood of positive clinical outcomes.

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Field: Pharmacology

PharmacologyMedicine