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PEDIATRICS· 2012Q1

Diagnosis and Management of Childhood Obstructive Sleep Apnea Syndrome

Carole L. Marcus, Lee J. Brooks, Kari A. Draper, David Gozal et al.

Short summary

Childhood obstructive sleep apnea syndrome (OSAS) affects 0-5.7% of children, is linked to cardiovascular, growth, and neurobehavioral issues, and is best treated initially with adenotonsillectomy (AT), though residual OSAS can persist in 13-73% of cases.

AI-generated from the title and abstract; the full text is not read.

Key points

  • Childhood OSAS prevalence ranges from 0% to 5.7%, with obesity as an independent risk factor.
  • OSAS is associated with cardiovascular, growth, and neurobehavioral abnormalities, and possibly inflammation.
  • Adenotonsillectomy (AT) is the primary treatment, but residual OSAS can occur in 13-73% of patients post-surgery.
  • CPAP is effective but adherence is a major barrier, making it a second-line therapy.
  • Diagnostic screening tests for OSAS generally have low sensitivity and specificity.

AI-generated from the title and abstract; the full text is not read.

Abstract

OBJECTIVE: This technical report describes the procedures involved in developing recommendations on the management of childhood obstructive sleep apnea syndrome (OSAS). METHODS: The literature from 1999 through 2011 was evaluated. RESULTS AND CONCLUSIONS: A total of 3166 titles were reviewed, of which 350 provided relevant data. Most articles were level II through IV. The prevalence of OSAS ranged from 0% to 5.7%, with obesity being an independent risk factor. OSAS was associated with cardiovascular, growth, and neurobehavioral abnormalities and possibly inflammation. Most diagnostic screening tests had low sensitivity and specificity. Treatment of OSAS resulted in improvements in behavior and attention and likely improvement in cognitive abilities. Primary treatment is adenotonsillectomy (AT). Data were insufficient to recommend specific surgical techniques; however, children undergoing partial tonsillectomy should be monitored for possible recurrence of OSAS. Although OSAS improved postoperatively, the proportion of patients who had residual OSAS ranged from 13% to 29% in low-risk populations to 73% when obese children were included and stricter polysomnographic criteria were used. Nevertheless, OSAS may improve after AT even in obese children, thus supporting surgery as a reasonable initial treatment. A significant number of obese patients required intubation or continuous positive airway pressure (CPAP) postoperatively, which reinforces the need for inpatient observation. CPAP was effective in the treatment of OSAS, but adherence is a major barrier. For this reason, CPAP is not recommended as first-line therapy for OSAS when AT is an option. Intranasal steroids may ameliorate mild OSAS, but follow-up is needed. Data were insufficient to recommend rapid maxillary expansion.

The authors' abstract, as published at the source. PEDIATRICS, 2012 · DOI ↗

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Field: Physiology

PhysiologyMedicine